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Active Research Studies for GASTROINTESTINAL PRIMARIES
Adjuvant Carcinoma of the Colorectal
ECOG E5202
A Randomized, Phase III Study Comparing 5-FU, Leucovorin and
Oxaliplatin versus 5-FU, Leucovorin, Oxaliplatin and Bevacizumab in
Patients with Stage II Colon Cancer at High Risk for Recurrence to
Determine Prospectively the Prognostic Value of Molecular Markers
CINJOG 070806 Autophagy and Anti-Angiogenesis in Metastatic Colorectal Carcinoma: A Phase II
Trial of Hydroxychloroquine to Augment Effectiveness of XELOX- Bevacizumab
"No prior chemo for metastatic disease"
May have a history of prior malignancy provided there is NED & not on treatment including hormonal
Therapy
Bevacizumab (IV) and Oxaliplatin (IV) – Day 1 of a 21 day cycle
Capecitabine D1-15
Hydroxychloroquine daily D1-21
ECOG N0147 Stage III Colon Cancer after Curative resection
Phase III trial FOLFOX with or without Cetuximab

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